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Cell-based three-dimensional systems are desirable in the field of high throughput screening assays due to their potential similarity to in vivo environment. We have used SH-SY5Y human neuroblastoma cells cultured in 3-D collagen hydrogel, confocal m...
Periodical:  Biosens Bioelectron  2005/08/09
Authors:  Desai, A., Kisaalita, W. S., Keith, C., Wu, Z. Z.
Keywords:  Actins/analysis, Cell Culture Techniques, Cell Differentiation, Cell Line, Tumor, Cell Movement/drug effects, Cells, Cultured, Coculture Techniques, Collagen Type I/physiology, Colonic Neoplasms/*pathology, Epidermal Growth Factor/*pharmacology, Fibroblast Growth Factor 2/pharmacology, Fibroblasts/cytology/drug effects/*physiology, Humans, Microfilaments/drug effects/ultrastructure, Neoplasm Invasiveness, rho GTP-Binding Proteins/metabolism, Transforming Growth Factor beta/*pharmacology

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