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Transforming growth factor-beta 1 (TGF-beta 1) is angiogenic in vivo. In two-dimensional (2-D) culture systems microvascular endothelial cell proliferation is inhibited up to 80% by TGF-beta 1; however, in three-dimensional (3-D) collagen gels TGF-be...
Periodical:  J Cell Physiol  1990/01/01
Authors:  Merwin, J. R., Anderson, J. M., Kocher, O., Van Itallie, C. M., Madri, J. A.
Keywords:  Cell Culture Techniques/*methods, Cell Division, Cell Line, Coculture Techniques, Collagen Type IV/metabolism, Cyclin-Dependent Kinase Inhibitor p21, Cyclins/metabolism, Extracellular Matrix, Fibroblasts/cytology/metabolism, Humans, Keratinocytes/*cytology/*metabolism, Keratins/metabolism, Mesoderm/cytology/metabolism, Phenotype, Proliferating Cell Nuclear Antigen/metabolism, Tumor Suppressor Protein p53/metabolism


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