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Cell-monolayer-based assays for chemotherapeutic drug discovery have proven to be highly artificial compared with physiological systems. The objective of this study was to culture cancer cells in a simple 3-dimensional (3D) collagen gel model to stud...
Periodical:  Assay Drug Dev Technol  2010/07/29
Authors:  Nirmalanandhan, V. S., Duren, A., Hendricks, P., Vielhauer, G., Sittampalam, G. S.

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